Design the bi-objective pharmaceutical supply chain network under uncertainty and considering the production, delivery, and drug perishable times

Authors

  • Mehrdad Mokhtari Department of Industrial Engineering, Payamnoor University, Tehran, Iran
Abstract:

In this paper, a bi-objective pharmaceutical supply chain network under uncertainty demand and transportation costs is modeled and developed. To control the uncertainty parameters, the robust optimization method is considering. The main objective of this paper determines the number and location of potential facilities such as drug manufacture centers and drug distribution centers by considering the minimizing the total costs and minimizing the maximum unsatisfied demand for distribution of drugs to demand zones. In this paper, production time, delivery, and drug perishable time is also considered in modeling. To solve the model, an example is designed and the multi-decision TH method is used. The results obtained the model shows this method is effective in finding the Pareto front at the right time. The results obtained the model shows this method is effective in finding the Pareto front at the right time.The results obtained the model shows this method is effective in finding the Pareto front at the right time.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

Green Supply Chain Network Design under Multi-mode Production and Uncertainty

A multi-periodic, multi-echelon green supply chain network consisting of manufacturing plants, potential distribution centers, and customers is developed. The manufacturing plants can provide the products in three modes including production in regular time, production in over time, or by subcontracting. The problem has three objectives including minimization of the total costs of the green supp...

full text

A possibilistic bi-objective model for a competitive supply chain network design under variable coverage

In this paper, the strategic planning of a supply chain under a static chain-to-chain competition on the plane is addressed. It is assumed that each retailer has a coverage area called the radius of influence. The demand of each demand zone is divided equally between the retailers which can cover that market. However, the demand of distant customers who are not in the retailers’ radius of influ...

full text

A Robust Supply Chain Network Design Considering Capacity, Supply and Delivery Distance Limits under Uncertain Demand

This paper presents a robust supply chain network design considering capacity, supply and delivery distance limits under uncertain demand. It aims to form a systematic solution including facility location and capacity design, supply plan, production plan and delivery plan. The uncertainty of demand is described by means of scenario approach. Following a multiple criteria evaluation, the optimal...

full text

Benders Decomposition Algorithm for Competitive Supply Chain Network Design under Risk of Disruption and Uncertainty

In this paper, bi-level programming is proposed for designing a competitive supply chain network. A two-stage stochastic programming approach has been developed for a multi-product supply chain comprising a capacitated supplier, several distribution centers, retailers and some resellers in the market. The proposed model considers demand’s uncertainty and disruption in distribution centers and t...

full text

Optimal design of supply chain network under uncertainty environment using hybrid analytical and simulation modeling approach

Models that aim to optimize the design of supply chain networks have gained more interest in the supply chain literature. Mixed-integer linear programming and discrete-event simulation are widely used for such an optimization problem. We present a hybrid approach to support decisions for supply chain network design using a combination of analytical and discrete-event simulation models. The prop...

full text

developing a bi-objective model of the closed-loop supply chain network design compatible with environment

closed-loop supply chain network (clscn) design aims at incorporating environmental considerations into the traditional supply chain design by including recycling, disassembly and reuse activities. in a clscn, the environmental considerations can also be facilitated by resorting to environmentally friendly materials and enhancing product reuse through the design of an appropriate product recove...

full text

My Resources

Save resource for easier access later

Save to my library Already added to my library

{@ msg_add @}


Journal title

volume 6  issue 26

pages  131- 144

publication date 2020-10-22

By following a journal you will be notified via email when a new issue of this journal is published.

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023